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Mitochondria is the powerhouse of cells.


There is no remaining original DNA of the very first organisms on Earth. People normally say that things like mitochondria (mtDNA) are not changing. But actually, there are mutations also in that DNA. When electromagnetic or chemical stress impacts the DNA that causes changes in its structure. This is one of the reasons why we cannot restore things like T-Rex to nature. We can take the DNA of that dinosaur and put that DNA in some other reptilians morula. In that process, we must just change the DNA in the cell's nucleus.

 But the problem is nobody knows how much damage is in that DNA. Nobody has ever seen a living T-Rex, and that means. No DNA can compare with the DNA sequences used in that work. Without full DNA from the living organism, there is no DNA matrix. If we want to fix those damages in genomes by using sequences taken from some chicken that thing will not work as we want. 

The problem is that nobody knows what DNA sequences are missing. So genetic engineers can create something that looks like T-Rex, but that thing will not be T-Rex. The mitochondria DNA doesn't give very much data about the organism where they give energy. 

Mitochondria have different, own DNA. That has no connection with the specie's DNA. So mitochondria still have the form. That they had before they went into symbiosis with cells. When cells start to divide, the mitochondria get a signal that they must start to multiply. This thing brings a very interesting idea to my mind. 



"A human blastocyst-like synthetic embryo called blastoid showing the presence of an enveloping layer of extra-embryonic cells, a blastocoel-like cavity, epiblast cells (green, giving rise to the future embryo) and hypoblast cells (red, giving rise to the future amnion). iMiGSeq was used to sequence mtDNA in a single blastoid to model the dynamics of mtDNA mutations during human embryogenesis. Credit: © 2023 KAUST; Mo Li". (ScitechDaily.com/Maternally Inherited Diseases: New Technology Uncovers Hidden Mitochondrial DNA Mutations)






Above: Asterix cartoon (Image:https://asterix.com/en/the-collection/albums/asterix-the-gaul/)


The strength of muscle cells depends on the number of mitochondria in those cells. If genetic engineers can create muscle cells that are more mitochondria than usual those muscles will be stronger. 

Do you know the comics Asterix? The small Gallian village defends itself against the Romans by using a secret potion that gives supernatural strength to those people. The reason why those strengths come from the potion is that those people are easier to control. When the effect time of the potion is limited they need the potion again, if they wish to fight. 

There is a possibility that something can give a chemical signal to mitochondria that they must start to divide. But at this time the cell will not divide. That thing increases the power of the muscle cells. If researchers make this kind of chemical, there is a possibility that that kind of thing makes it possible to create superhumans. And when superhumans will not need those strengths anymore the extra-mitochondria could be destroyed. 

These kinds of things are interesting. And new technology allows the creation of cloned mitochondria that can inject into cells. Those cloned mitochondria can give immune cells superpowers. That allows them to destroy cancer cells. The cloned mitochondria can help to keep things like cells alive until they will get to the laboratory. That technology can make organ transfers more successful than they still are. 


https://scitechdaily.com/maternally-inherited-diseases-new-technology-uncovers-hidden-mitochondrial-dna-mutations/

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